Describe 2 experimentally important aspects of grid cell responses (in addition to the regular hexagonal pattern) which in your view can point to the possible underlying mechanism of grid cells’ hexagonal response pattern.

Q1. Grid cells are neurons in the medial entorhinal cortex (MEC) that fire at vertices of hexagonal lattices tessellating an environment.

  • Describe 2 experimentally important aspects of grid cell responses (in addition to       the regular hexagonal pattern) which in your view can point to the possible underlying       mechanism of grid cells’ hexagonal response pattern. (10 points)
  • Describe the oscillatory-interference model of grid cells. Argue for and against the model taking into account the experimental data that exists in the literature. (10 points)
  • Since a grid cell fires at the vertices of a hexagonal grid, there would be ambiguity in inferring the position of the animal from the response of one cell (when a grid cell fires, the animal can be in any of the vertices of that grid cell). Do you think that one can infer the position of an animal by looking at response of a population of grid cells? (10 point)

Q2. Suppose that 4 stimuli (A, B, C and D) are presented to an animal with equal probabilities, while a fifth stimulus, E, is presented with twice the probability of the other 4. The table below shows the probability of different spike counts recorded in the experiment in response to each of these stimuli.

stimulus/response 5 spikes 10 spikes 15 spikes 20   spikes
stimulus A 3/5 2/5 0 0
stimulus B 2/5 3/5 0 0
stimulus C 1/4 1/4 1/4 1 / 4
stimulus D 0 0 1/2 1 / 2
stimulus E 1/2 0 0 1 / 2
  • What is the entropy of stimulus set? (5 points )
  • What is the entropy of the responses? (5 points )
  • What is the stimulus response mutual information? (10)
  • Assume that after these measurements, someone shows one of the stimuli to the animal. If 20 spikes are recorded in response to this stimulus, what would be your best guess for which stimulus was presented? (10)

Q3. (a) Describe what noise correlation (5 points) and signal correlation (5 points) mean.         (b) Take a case of positive or negative noise and signal correlations between two cells. Discuss the consequence that these correlations will have on the stimulus-response mutual information. (10 points)

Q4. How does the balance between inhibition and excitation in a recurrent network lead to irregular firing? In addition to the irregular firing, describe another consequence of the inhibition-excitation balance. (10 points)

Q5. Consider the following 3 layer network. The input values shown in ellipses on top of the figure are propagated through the network. The numbers next to each line show the synaptic weights and each neuronal transfer function is shown in a circle. As shown in the figure, neurons in the second layer are all binary neurons with threshold 1 except for the right most neuron which has a threshold of 0. Neurons in the second layer are thresholdlinear neurons with threshold at 1 and a gain of 1.

Calculate input to and the firing rate of each of the 5 neurons. (2 points each)

Place your order
(550 words)

Approximate price: $22

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
The price is based on these factors:
Academic level
Number of pages
Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.

Money-back guarantee

You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.

Read more

Zero-plagiarism guarantee

Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.

Read more

Free-revision policy

Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.

Read more

Privacy policy

Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.

Read more

Fair-cooperation guarantee

By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.

Read more