Ruggiero, M., Dauri, M., & Mariani, P. P (2009). Total Knee Replacement: Prevention of Deep-Vein Thrombosis Using Pharmacological (Low-Molecular-Weight Heparin) and Mechanical (Intermittent Foot Sole Pump System) Combined Prophylaxis. Preliminary Results. Summary of article: Giannoni et al. (2009) delved to establish the role of combined pharmacological and mechanical prophylaxis in preventing deep venous thrombosis following total knee replacement. Research elements: the researchers applied prospective case series study, and a total of 38 total knee replacement procedures were carried out on 34 patients, and four patients had bilateral TKR. The researchers gave patients injections of nadroparin calcium and these patients were then observed for 15 days. Outcomes/research results: the results obtained by Giannoni et al (2009) showed that nadroparin calcium reduced the incidence of DVT substantially. Significance to nursing and patient care: the findings of the study implied that nadroparin is effective in preventing DVT after TKR. As such, nadroparin should be the drug of choice by nurses in the prevention of DVT infections following TKR. Article 2: Blanchard, Y., Meuwly, P., Leyvraz, M., Miron., Bounameaux, H., Hoffmeyer, P., Didier, D., & Schneider, P. (2010).
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