Obstructive Sleep Apnea Author’s Name Institution Peker, Glantz, Thunstorm et al. (2008), conducted a randomized control trial seeking to demonstrate the design and rationale of CPAP therapy in patients with OSA and coronary artery disease. According to the authors, development of coronary heart disease significantly affected the prognosis of OSA. In the article, the authors report that OSA associated with heart disease resulted in 24% of deaths compared with 5% in patients without complications. Coronary heart disease is seen in an estimated 25% of patients who develop OSA. In the study, the authors demonstrated that the application of CPAP treatment was effective in preventing and improving the clinical course of heart disease. Although other treatment modalities were applied in the treatment of OSA, CPAP therapy was the first-line treatment approach which was effective in preventing the occurrence of heart diseases. Oliveira, Campos, Cintra et al. (2009) conducted a randomized control study seeking to establish the impact of Continuous Positive Airway Pressure (CPAP) treatment on left atrial function and volume in patients with Obstructive Sleep Apnea (OSA) using a real-time-three dimensional echocardiogram. According to the article, there is epidemiological data linking OSA to cardiovascular complications.
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