Tissue engineering


1) Tissue engineering

  1. What is the extracellular matrix composed of and how is it organized at the nanolevel? (10pts, 1 page)
  2. Stem cell fate is affected by the cell´s interaction with its surroundings. Describe the three general properties of the stem cell niche that control stem cell fate in vitro? (10pts, 1page)

2) Drug delivery (25pts)

  1. For what reasons do we need drug delivery systems? (5pts, ½ page)
  2. What are the cellular mechanisms responsible for uptake of micro/nanoparticles by cells? (20pts, 2pages)

3) Theranostics (30pts)

  1. What do we mean by theranostics? (5pts, ½ page)
  2. Outline briefly the working principle of Magnetic Resonance and Ultrasound in the biomedical context (10pts, 1page).
  3. You have made a nanoparticle with great potential for medical imaging and you are interested in testing the particle in people, but first you need to address the safety of the particle. Outline three of the most important in vitro test you have to do to be able to say something about the biocompatibility of your particle. (15pts, 2pages)

The semester paper is 25pts=100total.

Thank you.


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