Question 1 )
What is a nuclear receptor? Describe its domain structure and outline its general mechanism of action. Provide three examples of nuclear receptors.
Describe a mechanism that explains how intracellular cAMP levels can be controlled by receptor signalling.
Question 3 (7 points)
Describe mechanisms that contribute to innate immunity against
Describe how growth factor receptors are downregulated by endocytosis and lysosomal degradation.
a Dynamin b Voltage-gated Ca2+ channels c SNARE proteins
What is a stem cell? Describe two signalling pathways that contribute to expansion of the stem cell population. Which roles do the proteasomes play in these signalling pathways?
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